Thalidomide was developed by a German pharmaceutic company and originally used as a botheration killer and was proclaimed a wonder drug for insomnia, coughs, colds and headaches. It besides changes the bodys immune response and reduces the ability of the body to grow parvenue blood vessels. It was after-hoursr discovered that the drug could similarly salvage symptoms of morning sickness in significant women.
In the late 1950s, over 10,000 children in 46 disparate countries were innate(p) with deformities as a consequence of the use of thalidomide by mothers. Many Thalidomide babies were born with birth defects such as extremely short or missing arms and legs, missing ears (both outside and inside), and deafness. There is also a risk of other problems such as substance defects, missing or small eyes, paralysis of the face, kidney abnormalities, gastrointestinal abnormalities, poor growth and mental health issues.
The original tests on thalidomide did non show up the problem of birth defects as the savage tests carried out by the inventor of the drug were incomplete, and their clinical trials were hurriedly done and uncertain.
Also, before the introduction of thalidomide there were no savage tests carried out purposely to investigate teratogenic (malformation) effects or any tests to show the effects that the drug had on pregnant women and their babies.
Thalidomide led to tougher testing and drug approval procedures in some countries, including the United States and the United Kingdom. Regulators and companies must make sure a drug that is initially effective does not later sanction to be dangerous. That requires years of clinical trials on many divers(prenominal) cases. The drug is first tested on animals of all different cases then on humans. The effects of the drug are almost monitored over a long period of time, in case of any dangerous side effects. If the drug is deemed to be serious for people of all categories, it may be put on sale.
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